Microsoft Unveils Responses API and Computer-Using Agent in Azure AI Foundry

March 12, 2025

Details

  • Microsoft has introduced the Responses API and Computer-Using Agent (CUA) in Azure AI Foundry, enabling seamless integration of AI tools and automated graphical user interface interactions for enterprises as of March 2025.
  • The Responses API streamlines retrieval, reasoning, and action execution into singular API calls, simplifying file searches, code analysis, and coordination across multiple tools.
  • CUA allows agents to navigate and interact with GUIs using natural language, adapting on the fly to interface changes and removing the need for rigid automation scripts.
  • This builds on Microsoft's recent Azure AI Foundry updates announced at Build 2025, which also emphasize new security features like Entra Agent ID and expanded Purview compliance.
  • Initial use cases include automating tasks in customer service, IT operations, and supply chain management, with future integration planned for Windows 365 and Azure Virtual Desktop for cloud-based workflows.

Impact

With these launches, Microsoft strengthens its foothold in AI-driven enterprise automation, responding to increasing industry demand for secure, adaptive agentic solutions. The CUA’s flexible approach to legacy system integration could lower operational costs and streamline digital transformation. As organizations move toward automated workforces, Microsoft’s enhanced multi-agent orchestration is likely to shape best practices in regulated sectors.

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